AIRRC5 - LIBRA-seq: Linking antibody sequence to antigen specificity (I. Georgiev)
1.6 هزار بار بازدید -
4 سال پیش
-
Session from the "AIRR Community
Session from the "AIRR Community Meeting V – Zooming in to the AIRR Community!" (December 8-10, 2020)
The meeting covers progress reports from the AIRR-C Working Groups & Sub-committees, two scientific sessions (including four short talks chosen from the posters), two interactive poster sessions and four live software tool demonstrations.
https://www.antibodysociety.org/the-a...
Basic Science Session - Moderated by Jason Vander Heiden (Scientist, Genentech)
LIBRA-seq: Linking antibody sequence to antigen specificity
Ivelin Georgiev
Associate Professor, Vanderbilt University Medical Center
• LIBRA-seq is a technology for high-throughput mapping of BCR sequence to antigen specificity through sequencing.
• LIBRA-seq was initially validated on samples from two HIV-infected subjects, identifying both HIV- and influenza-specific B cells, predicting antigen reactivity for thousands of single B cells, and discovering a previously unknown broadly neutralizing HIV antibody.
• LIBRA-seq will be of utility for antibody discovery, vaccine evaluation, and antibody-antigen specificity characterization.
The meeting covers progress reports from the AIRR-C Working Groups & Sub-committees, two scientific sessions (including four short talks chosen from the posters), two interactive poster sessions and four live software tool demonstrations.
https://www.antibodysociety.org/the-a...
Basic Science Session - Moderated by Jason Vander Heiden (Scientist, Genentech)
LIBRA-seq: Linking antibody sequence to antigen specificity
Ivelin Georgiev
Associate Professor, Vanderbilt University Medical Center
• LIBRA-seq is a technology for high-throughput mapping of BCR sequence to antigen specificity through sequencing.
• LIBRA-seq was initially validated on samples from two HIV-infected subjects, identifying both HIV- and influenza-specific B cells, predicting antigen reactivity for thousands of single B cells, and discovering a previously unknown broadly neutralizing HIV antibody.
• LIBRA-seq will be of utility for antibody discovery, vaccine evaluation, and antibody-antigen specificity characterization.
4 سال پیش
در تاریخ 1399/09/27 منتشر شده
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