David Baker - Design of protein structures, functions and assemblies

Watch on LabRoots at: http://labroots.com/user/webinars/det...
I will describe  recent advances in computational protein design  which allow the generation of new protein structures  and functions.   I will describe the use of these methods  to design ultra-stable idealized proteins,  flu neutralizing proteins,  high affinity ligand binding proteins,  and self assembling protein nanomaterials.   I will discuss possible applications to therapeutics, vaccines and diagnostics.    I will also describe the contributions of the general public to these efforts through the distributed computing project  Rosetta@home and the online protein folding and design game FoldIt.