Salmonella Lifestyle Choices

Prof. Linda Kenney describes a recent project from her lab on Salmonella pathogenesis. In this study, MBI Senior Research Fellow Dr. Stuti Desai and colleagues discovered that the bacterial protein SsrB is the molecular switch for determining whether Salmonella infections become acute and virulent, or remain in a dormant carrier state. This study is published in eLife (Desai et al., The horizontally-acquired response regulator SsrB drives a Salmonella lifestyle switch by relieving biofilm silencing, February 2, 2016, eLife 2016; 5: e10747, doi: 10.7554/eLife.10747). mbi.nus.edu.sg/features/a-bacterial-molecular-swit…

• #education
• #mechanobiology
• #mechanobiology_institute
• #mbi
• #salmonella
• #gene_regulation
• #pathogenesis
• #infection
• #gene_silencing
• #biofilm
• #virulence