TMS Alcohol Protecting Group Using Silyl Ether
12.6 هزار بار بازدید -
2 سال پیش
-
https://Leah4sci.com/alcohol presents: TMS Protecting Group for Alcohol using a Silyl Ether - Reaction and Mechanism
📺Watch Next: Introduction to Alcohol Properties and Reactions Introduction to Alcohol Properties an...
Need help with Orgo? Download my free guide ’10 Secrets to Acing Organic Chemistry’ HERE: https://leah4sci.com/orgo-ebook/
In this video, you’ll learn how to protect the acidic proton of an alcohol from strongly basic reagents like alkynide ions and Grignard reagents by forming the trimethyl silyl ether using TMS-Cl. You’ll see a detailed breakdown of the reaction and mechanism of the alcohol protecting group - TMSO and learn how to deprotect the alcohol with the use of tetrabutyl ammonium fluoride - TBAF.
↪ Links & Resources Mentioned In This Video ↩
▸Alcohol Reactions Series + Cheat Sheet https://Leah4sci.com/Alcohol
▸Acetals and Ketals in Organic Chemistry https://Leah4sci.com/Acetal
▸Grignard Reaction and Mechanism https://Leah4sci.com/Grignard
▸Polar and Nonpolar Covalent Bonding Ionic, Polar Covalent and Non-Polar C...
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⏱ In this video:
[0:29] Why Protecting Groups are Used
[1:43] Ethers as Protecting Groups
[2:46] Structure of TMS
[3:06] Structure of TBAF
[3:32] Protecting Group Full Reaction and Mechanism
[5:37] Simplified Reaction and Mechanism
[7:30] Another Practice Example
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Follow along with your semester by using my Orgo Syllabus Companion: https://leah4sci.com/syllabus
For more in-depth review including practice problems and explanations, come join my online membership site, the Organic Chemistry Study Hall: https://leah4sci.com/join
❓Questions? Ask me here: https://Leah4sci.com/contact
👩🏫 For private online tutoring visit my website: https://leah4sci.com/organic-chemistry
Let’s connect:▸Instagram: Instagram: leah4sci
▸Facebook: Facebook: Leah4Sci
▸Twitter: Twitter: Leah4Sci
▸Pinterest: Pinterest: leah4sci
🔔 Subscribe to my channel so you don’t miss out on any new videos 🔔
https://leah4sci.com/youtube
🩺💉 My MCAT YouTube Channel: https://leah4sci.com/MCATyoutube 💉🩺
📺Watch Next: Introduction to Alcohol Properties and Reactions Introduction to Alcohol Properties an...
Need help with Orgo? Download my free guide ’10 Secrets to Acing Organic Chemistry’ HERE: https://leah4sci.com/orgo-ebook/
In this video, you’ll learn how to protect the acidic proton of an alcohol from strongly basic reagents like alkynide ions and Grignard reagents by forming the trimethyl silyl ether using TMS-Cl. You’ll see a detailed breakdown of the reaction and mechanism of the alcohol protecting group - TMSO and learn how to deprotect the alcohol with the use of tetrabutyl ammonium fluoride - TBAF.
↪ Links & Resources Mentioned In This Video ↩
▸Alcohol Reactions Series + Cheat Sheet https://Leah4sci.com/Alcohol
▸Acetals and Ketals in Organic Chemistry https://Leah4sci.com/Acetal
▸Grignard Reaction and Mechanism https://Leah4sci.com/Grignard
▸Polar and Nonpolar Covalent Bonding Ionic, Polar Covalent and Non-Polar C...
- - - - - - - - - - - - - - - - - - - - - - - -
⏱ In this video:
[0:29] Why Protecting Groups are Used
[1:43] Ethers as Protecting Groups
[2:46] Structure of TMS
[3:06] Structure of TBAF
[3:32] Protecting Group Full Reaction and Mechanism
[5:37] Simplified Reaction and Mechanism
[7:30] Another Practice Example
- - - - - - - - - - - - - - - - - - - - - - - -
Follow along with your semester by using my Orgo Syllabus Companion: https://leah4sci.com/syllabus
For more in-depth review including practice problems and explanations, come join my online membership site, the Organic Chemistry Study Hall: https://leah4sci.com/join
❓Questions? Ask me here: https://Leah4sci.com/contact
👩🏫 For private online tutoring visit my website: https://leah4sci.com/organic-chemistry
Let’s connect:▸Instagram: Instagram: leah4sci
▸Facebook: Facebook: Leah4Sci
▸Twitter: Twitter: Leah4Sci
▸Pinterest: Pinterest: leah4sci
🔔 Subscribe to my channel so you don’t miss out on any new videos 🔔
https://leah4sci.com/youtube
🩺💉 My MCAT YouTube Channel: https://leah4sci.com/MCATyoutube 💉🩺
2 سال پیش
در تاریخ 1400/11/26 منتشر شده
است.
12,607
بـار بازدید شده