Binding Sites for Regulatory RNA-Binding Proteins Identification | Protocol Preview

JoVE (Journal of Visualized Experiments)
JoVE (Journal of Visualized Experiments)
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Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins -  a 2 minute Preview of the Experimental Protocol

Ravinder Singh
University of Colorado at Boulder, Department of Molecular, Cellular and Developmental Biology;

Sequence specificity is critical for gene regulation. Regulatory proteins that recognize specific sequences are important for gene regulation. Defining functional binding sites for such proteins is a challenging biological problem. An iterative approach for identification of a binding site for an RNA-binding protein is described here and is applicable to all RNA-binding proteins.

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پارسال در تاریخ 1401/12/09 منتشر شده است.
258 بـار بازدید شده
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