Abnormality of Sweat Glands in Cystic Fibrosis
10.2 هزار بار بازدید -
5 سال پیش
-
Please read and agree to
Please read and agree to the disclaimer before watching this video.
. Cystic fibrosis is the most common hereditary disease which causes death in the United States, by the age of 20 or 30.
Dr. Mobeen Syed discusses the abnormalities in the genes which lead to cystic fibrosis.
The three genes responsible for phenylalanine production are located on the chromosome no. 7. These genes are also responsible for contributing proteins to CFTR complex. The CFRT complex is a transmembrane regulator chloride channel.
***In cystic fibrosis, the phenylalanine genes undergoes deletion.
***An abnormality in the phenylalanine genes causes abnormal production of CFTR complex.
The improperly folded protein complex (an abnormal CFTR complex) degrades in the Golgi apparatus.
***Normally what happens is that chloride, sodium, and water (small amount) are reabsorbed from the sweat when thrown out of the sweat glands in the sweat canaliculi. Result is that sweat becomes hypotonic.
On the other hand, chloride, sodium, and water are not reabsorbed from the sweat when the CFTR complex is abnormal. The result is that the sweat becomes hypertonic when released.
***The release of the hypertonic solution causes heat exhaustion and dehydration.
The following topics have discussed in the video:
* Definition of cystic fibrosis
* Normal sweat production
* Abnormality in the sweat gland
* Production of hypertonic sweat
* Effect of hypertonic sweat on the body ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
. Cystic fibrosis is the most common hereditary disease which causes death in the United States, by the age of 20 or 30.
Dr. Mobeen Syed discusses the abnormalities in the genes which lead to cystic fibrosis.
The three genes responsible for phenylalanine production are located on the chromosome no. 7. These genes are also responsible for contributing proteins to CFTR complex. The CFRT complex is a transmembrane regulator chloride channel.
***In cystic fibrosis, the phenylalanine genes undergoes deletion.
***An abnormality in the phenylalanine genes causes abnormal production of CFTR complex.
The improperly folded protein complex (an abnormal CFTR complex) degrades in the Golgi apparatus.
***Normally what happens is that chloride, sodium, and water (small amount) are reabsorbed from the sweat when thrown out of the sweat glands in the sweat canaliculi. Result is that sweat becomes hypotonic.
On the other hand, chloride, sodium, and water are not reabsorbed from the sweat when the CFTR complex is abnormal. The result is that the sweat becomes hypertonic when released.
***The release of the hypertonic solution causes heat exhaustion and dehydration.
The following topics have discussed in the video:
* Definition of cystic fibrosis
* Normal sweat production
* Abnormality in the sweat gland
* Production of hypertonic sweat
* Effect of hypertonic sweat on the body ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
5 سال پیش
در تاریخ 1398/07/02 منتشر شده
است.
10,238
بـار بازدید شده