Flu Vac in the Pandemic
110.4 هزار بار بازدید -
4 سال پیش
-
Seasonal InfluenzaCaused by influenza virusesPhoto
Seasonal Influenza
Caused by influenza viruses
Photo Credit: Cynthia Goldsmith Content Providers(s): CDC/ Dr. Terrence Tumpey. X 100,000
CDC
https://www.cdc.gov/flu/weekly/index.htm
UK, 2020 - 2021
https://www.england.nhs.uk/wp-content...
the national flu immunisation programme will be absolutely essential to protecting vulnerable people
and supporting the resilience of the health and care system
Mild to severe illness
Higher viral doses, the more sick people became
https://academic.oup.com/cid/article/...
Old, young, co-morbidities
https://www.cdc.gov/flu/about/burden/...
Annually (US) since 2010
9 million – 45 million illnesses
140,000 – 810,000 hospitalizations
12,000 – 61,000 deaths
https://www.hopkinsmedicine.org/healt...
Clinical features in children
Fever, which may be as high as 103°F (39.4°C) to 105°F (40.5°C)
Body aches, which may be severe
Headache
Sore throat
Cough that gets worse
Tiredness
Runny or stuffy nose
Nausea
Vomiting
Diarrhea
Possible complications in children
Pneumonia
Dehydration
Salts (electrolytes)
Worsening of long-term medical problems
Brain dysfunction such as encephalopathy
Sinus problems and ear infections
In rare cases, death
Initial concern
Increased Risk of Noninfluenza Respiratory Virus Infections Associated With Receipt of Inactivated Influenza Vaccine (Clinical Infectious Diseases, 2012)
https://www.ncbi.nlm.nih.gov/pmc/arti...
We were able to observe a statistically significant increased risk of confirmed noninfluenza respiratory virus infection among TIV recipients
Covid-19: Risk of death more than doubled in people who also had flu, English data show
https://www.bmj.com/content/370/bmj.m...
Odds of death were 2.27 times higher than in people with SARS-CoV-2 alone
possible synergistic effects in coinfected people
Safety of Influenza Vaccine during COVID-19 (September 2020, Journal of Clinical and Translational Science, Cleveland Clinic)
https://www.cambridge.org/core/journa...
The convergence with influenza season could result in significant morbidity and mortality
Patients (n = 18,868) tested for COVID-19
4,138 flu vac, 2019-2020
9,082 not flu vaccinated
Vaccinated group
Higher BMI
On more meds
More co-morbidities
Older
Blood work
Is someone had flu vac and tested positive for SARS-CoV-2
Unadjusted analysis shows:
Vaccinated individuals were less likely to test positive for SARS-CoV-2
More likely to be hospitalized
More likely to be admitted to the ICU and die during hospitalization
But, once adjusted
Influenza vaccination was unrelated to incidence of SARS- CoV-2 infection
Increased risk for worse hospital outcomes was not related to influenza vaccination
In people with COVID-19, influenza vaccination did not impact risk for hospitalization
Or ICU admission
Or hospital mortality
Overall
Influenza vaccination does not increase the incidence of COVID-19
or worsen the related morbidity or mortality
Providing reassurance that the vaccination strategy for global influenza should proceed as planned during the COVID-19 pandemic
Surveillance data needs to be prospectively collected in fall 2020
Study the outcome of concurrent SARS-CoV-2 and influenza infection
Assess any interaction between influenza vaccinations, a newly developed vaccine against coronavirus, influenza and COVID-19 infection
Odds of death were 2.27 times higher than in people with SARS-CoV-2 alone
Caused by influenza viruses
Photo Credit: Cynthia Goldsmith Content Providers(s): CDC/ Dr. Terrence Tumpey. X 100,000
CDC
https://www.cdc.gov/flu/weekly/index.htm
UK, 2020 - 2021
https://www.england.nhs.uk/wp-content...
the national flu immunisation programme will be absolutely essential to protecting vulnerable people
and supporting the resilience of the health and care system
Mild to severe illness
Higher viral doses, the more sick people became
https://academic.oup.com/cid/article/...
Old, young, co-morbidities
https://www.cdc.gov/flu/about/burden/...
Annually (US) since 2010
9 million – 45 million illnesses
140,000 – 810,000 hospitalizations
12,000 – 61,000 deaths
https://www.hopkinsmedicine.org/healt...
Clinical features in children
Fever, which may be as high as 103°F (39.4°C) to 105°F (40.5°C)
Body aches, which may be severe
Headache
Sore throat
Cough that gets worse
Tiredness
Runny or stuffy nose
Nausea
Vomiting
Diarrhea
Possible complications in children
Pneumonia
Dehydration
Salts (electrolytes)
Worsening of long-term medical problems
Brain dysfunction such as encephalopathy
Sinus problems and ear infections
In rare cases, death
Initial concern
Increased Risk of Noninfluenza Respiratory Virus Infections Associated With Receipt of Inactivated Influenza Vaccine (Clinical Infectious Diseases, 2012)
https://www.ncbi.nlm.nih.gov/pmc/arti...
We were able to observe a statistically significant increased risk of confirmed noninfluenza respiratory virus infection among TIV recipients
Covid-19: Risk of death more than doubled in people who also had flu, English data show
https://www.bmj.com/content/370/bmj.m...
Odds of death were 2.27 times higher than in people with SARS-CoV-2 alone
possible synergistic effects in coinfected people
Safety of Influenza Vaccine during COVID-19 (September 2020, Journal of Clinical and Translational Science, Cleveland Clinic)
https://www.cambridge.org/core/journa...
The convergence with influenza season could result in significant morbidity and mortality
Patients (n = 18,868) tested for COVID-19
4,138 flu vac, 2019-2020
9,082 not flu vaccinated
Vaccinated group
Higher BMI
On more meds
More co-morbidities
Older
Blood work
Is someone had flu vac and tested positive for SARS-CoV-2
Unadjusted analysis shows:
Vaccinated individuals were less likely to test positive for SARS-CoV-2
More likely to be hospitalized
More likely to be admitted to the ICU and die during hospitalization
But, once adjusted
Influenza vaccination was unrelated to incidence of SARS- CoV-2 infection
Increased risk for worse hospital outcomes was not related to influenza vaccination
In people with COVID-19, influenza vaccination did not impact risk for hospitalization
Or ICU admission
Or hospital mortality
Overall
Influenza vaccination does not increase the incidence of COVID-19
or worsen the related morbidity or mortality
Providing reassurance that the vaccination strategy for global influenza should proceed as planned during the COVID-19 pandemic
Surveillance data needs to be prospectively collected in fall 2020
Study the outcome of concurrent SARS-CoV-2 and influenza infection
Assess any interaction between influenza vaccinations, a newly developed vaccine against coronavirus, influenza and COVID-19 infection
Odds of death were 2.27 times higher than in people with SARS-CoV-2 alone
4 سال پیش
در تاریخ 1399/07/23 منتشر شده
است.
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