Macrolides ; Mechanism of action 【USMLE, Biochemistry】
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5 سال پیش
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Do you know how macrolides
Do you know how macrolides antibiotics work?
They inhibit prokaryotic translation elongation by
1. preventing translocation
2. blocking peptidyl-transfer
3. dissociation of peptidyl-tRNA from the ribosome.
#biochemistrynotes #antibiotics #pharmacologymadeeasy
(Reference) I express my gratitude and respect for your wonderful achievements.
1. Macrolide Antibiotics-an overview| ScienceDirect Topics.
ScienceDirect sciencedirect.com
From: Kendig's Disorders of the Respiratory Tract in Children (Ninth Edition), 2019
2. T. Kaneko, T.V. Magee
Therapeutic Areas II: Cancer, Infectious Diseases, Inflammation & Immunology and Dermatology
Comprehensive Medicinal Chemistry II, 2007
3. Purnima Kumar.
Chemistry and classification (Table 33-7; Fig. 33-8)
Pharmacology and Therapeutics for Dentistry (Seventh Edition), 2017
4. Watkins VS1, Polk RE, Stotka JL.
Drug interactions of macrolides: emphasis on dirithromycin.
Ann Pharmacother. 1997 Mar;31(3):349-56.
(Pictures) I express my gratitude and respect for your wonderful achievements.
1. Yikrazuul.
Erythromycin A
File:Erythromycin A.svg
2. Gareth J. Sanger & John B. Furness
Review Article | Published: 22 September 2015
Ghrelin and motilin receptors as drug targets for gastrointestinal disorders.
Nature Reviews Gastroenterology & Hepatologyvolume13,pages38–48 (2016)
3. Chlamydia pneumoniae
Eutensist
File:Chlamydia pneumoniae.jpg
4. Mycoplasma pneumoniae
Disease-Pathogenesis for Labs/CDC
cdc.gov
5. Ureaplasma species
Rose M. Viscardi, M.D.
Ureaplasma species; Role in Disease of Prematurity
Clin Perinatol. 2010 Jun; 37(2): 393–409.
doi: 10.1016/j.clp.2009.12.003
6. Legionella pneumophila
Public Health Image Library (PHIL)
phil.cdc.gov
7. campyrobacterium jejuni
De Wood, Pooley, USDA, ARS, EMU. - Agricultural Research Service (ARS) is the U.S. Department of Agriculture's chief scientific research agency.
File:ARS Campylobacter jejuni.jpg
8. H.pyrori
Cause, symptoms, and stomach ulcers
medicalnewstoday.com
9. ear
pixabay.com
(Opening Movie)
light house; Pixabay pixabay.com
music; Seashore Synthetic. OtoLogic. https://otologic.jp
(Music) Youtube free music
They inhibit prokaryotic translation elongation by
1. preventing translocation
2. blocking peptidyl-transfer
3. dissociation of peptidyl-tRNA from the ribosome.
#biochemistrynotes #antibiotics #pharmacologymadeeasy
(Reference) I express my gratitude and respect for your wonderful achievements.
1. Macrolide Antibiotics-an overview| ScienceDirect Topics.
ScienceDirect sciencedirect.com
From: Kendig's Disorders of the Respiratory Tract in Children (Ninth Edition), 2019
2. T. Kaneko, T.V. Magee
Therapeutic Areas II: Cancer, Infectious Diseases, Inflammation & Immunology and Dermatology
Comprehensive Medicinal Chemistry II, 2007
3. Purnima Kumar.
Chemistry and classification (Table 33-7; Fig. 33-8)
Pharmacology and Therapeutics for Dentistry (Seventh Edition), 2017
4. Watkins VS1, Polk RE, Stotka JL.
Drug interactions of macrolides: emphasis on dirithromycin.
Ann Pharmacother. 1997 Mar;31(3):349-56.
(Pictures) I express my gratitude and respect for your wonderful achievements.
1. Yikrazuul.
Erythromycin A
File:Erythromycin A.svg
2. Gareth J. Sanger & John B. Furness
Review Article | Published: 22 September 2015
Ghrelin and motilin receptors as drug targets for gastrointestinal disorders.
Nature Reviews Gastroenterology & Hepatologyvolume13,pages38–48 (2016)
3. Chlamydia pneumoniae
Eutensist
File:Chlamydia pneumoniae.jpg
4. Mycoplasma pneumoniae
Disease-Pathogenesis for Labs/CDC
cdc.gov
5. Ureaplasma species
Rose M. Viscardi, M.D.
Ureaplasma species; Role in Disease of Prematurity
Clin Perinatol. 2010 Jun; 37(2): 393–409.
doi: 10.1016/j.clp.2009.12.003
6. Legionella pneumophila
Public Health Image Library (PHIL)
phil.cdc.gov
7. campyrobacterium jejuni
De Wood, Pooley, USDA, ARS, EMU. - Agricultural Research Service (ARS) is the U.S. Department of Agriculture's chief scientific research agency.
File:ARS Campylobacter jejuni.jpg
8. H.pyrori
Cause, symptoms, and stomach ulcers
medicalnewstoday.com
9. ear
pixabay.com
(Opening Movie)
light house; Pixabay pixabay.com
music; Seashore Synthetic. OtoLogic. https://otologic.jp
(Music) Youtube free music
5 سال پیش
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