#29 - Altitude training and hypoxic conditioning with Dr Grégoire Millet

Dr Glenn McConell chats with Professor Grégoire Millet from the University of Lausanne in Switzerland. He is an absolute world leader in research into altitude training and hypoxic conditioning. This area has progressed greatly from Live High-Train High (LHTH) to Live High-Train Low (LHTL), LLTH and LHTL (and High). The type of attitude training/hypoxic conditioning one would undertake depends on if training for endurance or team sports. We also discussed using low oxygen (hypoxia) and high oxygen (hyperoxia) for health benefits.

0:00. Introduction and Grégoire’s background
4:58. History of altitude training
Mexico Olympics. Live High-Train High (LHTH).
6:52. Many combinations of altitude training
LHTH, Live High-Train Low (LHTL),
LLTH, LHTL (and High)
9:45. Altitude and oxygen availability
12:45. Altitude vs breathing low oxygen: not the same
14:32. Immediate responses to hypoxia
Increased breathing rate and heart rate, dehydration etc.
20:12. Lower VO2 max at altitude
Lower max HR. Normal efficiency.
24:39. Absolute vs relative exercise intensity
25:46. Placebo effect?
28:45. Long-term responses to altitude
Red blood cells, hemoglobin, mitochondria, capillaries.
32:24. Need to exercise for optimal adaptations in muscle
33:34. LHTL
Ben Levine.
36:19. LLTH
41:34. Health effects of LLTH
Positive blood vessel effects
43:04. Repeated sprints in hypoxia (RSH)
45:29. LLTH and improved blood vessel function
Endothelial function etc.
47:54. Health effects of low and high oxygen
Hypoxia and hyperoxia. Leptin, weight loss.
54:50. Hypoventilation at low lung volume (VHL) to cause hypoxia
59:00. VO2 max training at altitude
1:00:55. Use more carbohydrate during exercise at altitude
1:02:30. Greater sympathetic activation (adrenaline etc) at altitude
1:04:52. Oxidative stress/ Reactive oxygen species
1:08:42. What doesn’t kill you makes you stronger
1:10:12. Manipulating repeated sprints duration to alter aerobic/anaerobic contributions
1:13:20. Specificity of training to achieve required outcomes
1:13:51. LHTL (and High) in Rugby players
1:17:40. LHTL and LHTL (and High) for endurance
1:19:09. Ultramarathon star Killian Jornet and altitude training
1:21:15. Controversies in the area
1:24:47. Health benefits the most exciting for him
1:25:37. Outro (9 secs)

Inside Exercise brings to you the who's who of exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.

The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.

He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.100....

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