Mechanism of Insulin Secretion

Nonstop Neuron
Nonstop Neuron
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Video Summary:
Insulin is released by β cells of the pancreas. An increase in blood glucose leads to increased glucose entry in the cell. Its metabolism produces ATPs. Increased ATP level causes closure of ATP-sensitive K channel. This leads to depolarization and thereby opening of voltage-gated Ca channels. Ca influx through these channel increases intracellular Ca which in turn causes exocytosis of insulin vesicles.

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3 سال پیش در تاریخ 1400/01/09 منتشر شده است.
37,067 بـار بازدید شده
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