Combinations for Treatment-Resistant Depression

NEI Psychopharm
NEI Psychopharm
16.8 هزار بار بازدید - 2 سال پیش - Learn the essentials of psychopharmacology
Learn the essentials of psychopharmacology from Dr. Stephen Stahl! This clip from Stahl’s Essential Psychopharmacology, Video Edition covers potential treatment options for treatment-resistant depression. Learn more: https://nei.global/epvideos

Triple-action combo, such as SSRI/SNRI plus NDRI.  Selective serotonin reuptake inhibitor (SSRI) plus a norepinephrine dopamine reuptake inhibitor (NDRI) leads to a single boost for serotonin (5HT), norepinephrine (NE), and dopamine (DA). Serotonin norepinephrine reuptake inhibitor (SNRI) plus a norepinephrine dopamine reuptake inhibitor (NDRI) leads to a single boost for serotonin (5HT), a double boost for norepinephrine (NE), and a single boost for dopamine (DA).

California rocket fuel: SNRI plus mirtazapine. Combining a serotonin norepinephrine reuptake inhibitor (SNRI) with mirtazapine is a combination that has a great degree of theoretical synergy: 5HT is quadruple-boosted (with reuptake blockade, alpha 2 antagonism, 5HT2A antagonism, and 5HT2C antagonism), NE is quadruple-boosted (with reuptake blockade, alpha 2 antagonism, 5HT2A antagonism, and 5HT2C antagonism), and there may even be a double boost of dopamine (with 5HT2A and 5HT2C antagonism).

About: In Stahl’s Essential Psychopharmacology: Video Edition, the newly published fifth edition of the landmark textbook comes to life as Dr. Stahl himself presents every chapter with fully animated illustrations. Learn more: https://nei.global/epvideos

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2 سال پیش در تاریخ 1400/12/24 منتشر شده است.
16,838 بـار بازدید شده
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