Nitroglycerin - Uses, Side Effects, Safety - Doctor Explains

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In this video we will cover everything you need to know about Nitroglycerin, also known as Nitro. We will discuss how and when to use it, we will cover its side effects, dosage and much, much more.

You can find more usefull videos on cardiovascular diseases and their treatments here:
Cardiovascular Diseases And Treatments

Generic name: Nitroglycerin.
Brand names: Nitro and Nitrolingual.
Available as spray, injection and patch.

How to use it?
- Spray: first take a rest. If your chest pain does NOT subsides use the spray. Do so by sitting down, press your tongue against the roof of your mouth and hold your breath. Then spray under the tongue and close your mouth. DO NOT inhale the spray. The drug should starts to work almost immediately. However if necessary, you can spray another puff after five minutes.
Contact a doctor immediately if the pain has not disappeared after three uses and after 15 minutes. This could indicate a heart attack.
- Patch: peel off the protective film and try not to touch the adhesive with your fingers. Apply the patch to a clean, dry, undamaged and not too hairy area on your chest or on the inside of the upper arm.

When to use it?
Nitroglycerin are part of a group of drugs called nitrates. These can cause vasodilation (which is the widening of your blood vessels), lowering the central venous pressure and decreases the supply of blood to the heart. That is why nitroglycerin can be used in the treatment of:
- Acute attacks of angina pectoris, which is a medical term for chest pain or heart cramp.
- And offlabel it is used in the treatment of acute heart failure and Acute coronary syndrome.

What is the correct dosage?
The precise dose will depend on your specific indication of use, the side effect you might experience and the severity of your symptoms. Therefore always use the precise amount and frequency your doctor prescribed you.
- However, when treating angina pectoris in adults with a spray your doctor might prescribe a dose of 1–2 sprays under the tongue. Which can be repeated after 5 minutes if necessary.
- When your doctor prescribed you nitroglycerin as a patch, the usual dose for an adult would be a patch of 5 mg per day. If necessary this can be increased up to a patch of 10 or 15mg per day.

What are the side-effects?
- Very common (10%): headache, nausea, vomiting.
- Common (1-10%): dizziness, low blood pressure, sleepiness, a fast heart rate.
- Uncommon (0.1-1%): Worsened symptoms of angina pectoris, collapse, allergic skin reactions.
- Rare (0.01-0.1%): transient redness of the face and neck.
- Very rare (0.01%): heartburn and exfoliative dermatitis.

Safety:
First of all nitroglycerin can cause dizziness. Which can make it dangerous to drive.
Furthermore if you combine it with alcohol, this might further increase some of the side effects you might experience.
In addition nitroglycerin can have interactions with other drugs your are taking. Always discuss this with your prescribing doctor.
Lastly, nitroglycerin can be dangerous for pregnant women and women who are breast feeding. Therefore always discuss this with your personal doctor.

- Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. -

I want to give special thanks to my sponsors on Patreon:
- Sebastian Houwing: Investor

Literature:
1: Farmacotherapeutisch Kompas. (2022). Nitroglycerine.
2: Apotheek.nl (2022). Nitroglycerine.

* The images in this video are used for educational purposes only. Most of the images and videos in this video come from https://www.canva.com/.

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2 سال پیش در تاریخ 1401/02/21 منتشر شده است.
60,737 بـار بازدید شده
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