6. IRON- Iron proteins, functions, Sources, RDA, Absorption, transport, storage, anemia

total body iron 3 to 5 gm
75% in Hb
other iron containing proteins
Mb
cytochromes
cyt p-450
enzymes

RDA - 10 to 20mg
Sources
leafy veg, jaggery, cereals, pulses, liver, meat

Functions
transport of Oxygen and carbon dioxide
antioxidant
detoxification
cellular respiration

absorption
from duodenum and jejunum
DMT1
Ferroportin

transport form- transferrin in blood
storage form- Ferritin in liver, spleen, bone marrow, mucosal cell

Disease states
1. Iron deficiency anemia
2. Hemosiderosis
3. Hemochromatosis

• #education
• #biochemistry_by_dr_rajesh_jambhulkar