Rapamycin proves both good and bad for aging in human cells

Sasaki, et al. “Rapamycin promotes endothelial–mesenchymal transition during stress-induced premature senescence through the activation of autophagy.” CCS (2020) Read the article: https://doi.org/10.1186/s12964-020-00533-w Video produced by https://www.researchsquare.com/researchers/videos

• #science_technology
• #cell_communication_and_signaling
• #tokyo_metropolitan_institute_of_gerontology
• #rapamycin
• #senescence_associated_secretory_phenotype
• #endothelial_cells
• #stress_induced_premature_senescence
• #endothelial_mesenchymal_transition
• #autophagy
• #anti_aging
• #blood_vessels
• #oxidative_stress
• #hydrogen_peroxide
• #coronary_artery
• #polymer_chain_reaction
• #intercellular_adhesion_molecule_1
• #ganglioside_gm1
• #leukocytes
• #adhesion_assay
• #immunostaining
• #tgf_pathway